Motorists are advised to avoid Great Ancoats Street in Manchester following a serious collision.
Shortly after 1.20pm on Monday 17 December 2012, police were called to Great Ancoats Street near the Central Retail Park following reports of a collision.
Officers attended and found that a Volkswagen Polo had been in collision with a pedestrian, a woman believed to be in her 30s.
The woman has been taken to hospital where her condition is described as being serious.
A man has been arrested on suspicion of dangerous driving and remains in custody.
Great Ancoats Street is closed in both directions between the Central Retail Park and Oldham Road.
Enquiries are ongoing.
Anyone with information is asked to call police on 0161 856 4741.