Concern is growing for a woman who is missing from home.
Kimberley Louise Brown, aged 38, has not been seen since 3pm on 26 July 2012, when she left her home on Birchfields Road in Longsight.
She has never been reported missing before.
It is believed that Kimberley could be anywhere in Greater Manchester.
She is 5ft 7in tall and of medium build.
Detective Inspector Kevin Marriott said: “Since Kimberley was reported missing, we have launched a major investigation to trace her.
“As it has now been over a week since she was seen, we are becoming increasingly concerned for her welfare.
“I would urge anyone who may have seen Kimberley to call us, and my message to Kimberley is that if she sees this appeal, she should please contact us to tell us she is OK.”
Anyone with information is asked to call police on 0161 856 4146.