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John Winterton, 26, was last seen about 3am on Wednesday 18 August on Sale Road.
John is described as a white male; around 5 ft 8 to 6 ft tall, of medium build with brown short hair.
He was last seen wearing khaki green work pants with a rip on the right leg, dark brown Stanley work boots, white top with writing, a navy blue hoodless jacket and a black cap.
He has a tattoo on his right forearm of a clock and roses and a tattoo on his left upper arm of a tiger.
In a heartfelt appeal for his return, John's mother Debbie said: "John if you're reading this then please come home. My heart is breaking.
"Whatever it is you're worried about, we will support you. We want you to be happy and safe. When you're back home, I promise I'll take you to the caravan in Anglesey, you can spend as long as you want there, you can teach me how to fish and we can spend some time together.
"Even if you don't want to come home right now then that's ok, but please, just get in contact with someone to let us know you're ok. We all love and miss you son.
"If anyone reading this knows of any information that might help us find our John, please get in touch. Anything, however small, might lead us to getting our boy back safe. We just need our son, brother and uncle home.
"If you know anything at all, please contact the police. "
Anyone with information about John whereabouts is asked to contact police on 0161 856 6033 or 101.
Alternatively details can be passed via our LiveChat function at www.gmp.police.uk or via the independent charity Crimestoppers on 0800 555 111.