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Paul Mulcahy, who is 36-years-old, was last seen at Manchester Royal Infirmary at 7.15pm on Tuesday 10 September 2019.
He is believed to have a travel pass which allows him to use any bus, tram or train in the Greater Manchester area.
Paul Mulcahy is known to frequent the Moss Side, Rusholme and Stretford areas.
He is described as 6ft 2ins tall and of large build. He is believed to be wearing a green jumper, blue jeans and black trainers.
Anyone with information on his whereabouts is asked to contact police on
0161 856 4275 quoting reference 2742 of the 10/09/19.