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At around 5.00pm on 24 January 2021, a male in his late teens - was approached by a group of five other males, who were wielding knives, near to Longsight Medical Practice on Stockport Road.
The five males chased the victim and assaulted him, stabbing him in the chest.
The victim was taken to hospital for treatment and has since been discharged.
One arrest has been made and enquiries are ongoing.
Detective Sergeant Louise Kelly said: "This was a vicious attack which left the victim in hospital with a serious stab wound.
"This type of violence is completely unacceptable and will not be tolerated in Greater Manchester.
"We have been following numerous lines of enquiries and we are now coming to the public for their help to identify this male who we would like to speak to. It is believed that this man may be known by the nickname 'YS' or 'Young Shifty.'
"If you have any information at all about this individual, please get in touch with police as soon as possible so we can speak with him."
Anyone who can identify the male in this image, or has any information about the assault, should contact police on 0161 856 4409 quoting incident number 1988 of 24/01/2021.
Information can be passed on anonymously by calling the independent charity Crimestoppers on 0800 555 111.